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Chiroblog

The 4 New Subtypes of Autism

Posted: August 12, 2025
By: Dr. Drew Rubin

A groundbreaking 2025 study has revealed that autism includes four distinct subtypes, each with its own genetic and behavioral patterns. This research, based on data from over 5,000 children, helps explain why autism looks so different from person to person. For example, one group, called “Social/behavioral,” includes kids who have challenges with communication and repetitive behaviors but may reach developmental milestones on time. Another group, “Mixed ASD with Developmental Delay,” shows delays in early development but fewer emotional issues like anxiety. These differences are linked to specific genes that are active at different stages of brain development. The other two groups—“Moderate challenges” and “Broadly affected”—show varying levels of traits and genetic changes, with the latter having more intense symptoms from an early age.

For chiropractic patients and families, this means that understanding autism has become more personalized. Just like chiropractic care is tailored to each patient’s unique needs, autism support in our chiropractic setting now can be further customized based on a child’s subtype. We have been using the Polyvagal Theory since 2010 to help establish what particular protocol of care each child requires each visit, so the 4 new subtype categories can help enhance which direction care will proceed that day. As research continues, these insights could lead to better-targeted therapies and support systems, helping children thrive in ways that match their individual biology and development. 

References:

Four Autism Subtypes:  https://www.nature.com/articles/s41588-025-02224-z

Polyvagal Theory:  https://pmc.ncbi.nlm.nih.gov/articles/PMC9131189/

 

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