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Chiroblog

What is synaptic pruning?

Posted: June 16, 2025
By: Dr Rubin & Jamie Zinman

In its early stages as an infant, the human brain consists of a network of approximately 100 billion neurons. As we grow and develop, this network undergoes a process referred to as “synaptic pruning”, where excess neurons and synaptic connections are eliminated to enhance the efficiency of the more necessary neural circuits. Essentially, this process is the brain’s way of fine-tuning itself and ensuring that the most frequently used connections are strengthened which creates a more efficient and adaptable nerve system. It is the ultimate ‘use-it-or-lose-it’ process that the brain uses to create the best version of itself.  


Synaptic pruning in some cases can be disrupted. For instance, over-pruning and under-pruning have been linked to various neurological conditions such as autism, schizophrenia, and Alzheimer’s disease. Any sort of intervention that helps the brain learn and grow, from exercising to having new experiences and even chiropractic care, can improve neuroplasticity, which may help with pruning. 

Synaptic Pruning & Neural Wiring During Development

https://pmc.ncbi.nlm.nih.gov/articles/PMC7368197/

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